Endocrine Abstracts

Introduction: After the fast of the month of Ramadan, the lipid balance of the elderly patients with diabetes can be modified. The aim of our study was to describe the evolution of the parameters of the lipid balance after the fast of Ramadan in a population of elderly diabetic subjects.Patients and methods: This is a prospective evaluative study conducted in a population of 20 patients with type 2 diabetes aged over 65 years. This population had benefit...

Introduction: Few studies have examined the adherence to anti–diabetic treatment in patients with diabetes during the fast of the month of Ramadan.The aim of our study was to describe the adherence to antidiabetic treatment in patients with diabetes before and during the fast.Patients and Methods: This is a descriptive and analytical study carried out on 140 diabetics who have fasted the month of Ramadan. The risk stratificat...

Introduction: The advent of insulin analogs has significantly reduced the undesirable effects of human insulin, particularly hypoglycemia. Beneficial effects on the lipid balance have also been described. The aimof our study was to describe the evolution of the lipidic parameters after the switch on insulin analogs.Patients and Methods: This is a longitudinal retrospective study about 61 patients with type 2 diabetes, switched to insulin analogs since at...

Introduction: Pseudoxanthoma elasticum (PXE), a multisystem heritable disorder, is characterized by ectopic mineralization of soft connective tissues. It is an autosomal recessive disorder in which mutations in the ABCC6 gene result in low levels of inorganic pyrophosphate (PPi).In its classic form, PXE is a late-onset, slowly progressing disease, and the major clinical problems relate to development of vascular complications, including hypertension, int...

Introduction: Gestational diabetes mellitus (GDM) complicates approximately 3% to 9% of pregnancies. Diagnosis and treatment of GDM remain essential to limit maternal and neonatal outcomes. The aim of the study was to evaluate the difference in pregnancy outcomes between insulin- and diet-treated tunisian women with gestational diabetes.Methods: It was a prospective longitudinal study including 220 patients followed for GDM at the research unit of the C ...

Introduction: Dyslipidemia in type 1 diabetic patients is a frequent situation and seems to be a risk factor for the occurrence of degenerative complications. The aim of this study is to evaluate the lipid profile of type 1 diabetic patients and to study the relationship between dyslipedmia and the occurrence of degenerative complications.Method: This is a retrospective study conducted at the National Nutrition Institute of Tunis including 110 diabetic p...

Introduction: Body mass index (BMI) and gestational weight gain are increasing globally. However, the association between gestational weight gain consistent with the Institute of Medicine (IOM) guidelines and neonatal birth weight among women with gestationnel diabetes (GDM) remain unclear.Objective: The aim of our study was to assess gestational weight gain among tunisian women with GDM and his effect on neonatal birth weight.Meth...

Introduction: Gestational diabetes mellitus (GDM) is the most common metabolic disturbance during pregnancy. The prevalence of GDM is rising and correlates with the increase in maternal obesity over recent decades. The aim of our study was to assess the association between maternal insulin resistance with pregnacy outcomes and maternal characteristics among tunisians women with GDM.Methods: A prospective longitudinal study carried out during the year 202...

Introduction: Hypothyroidism is a frequent endocrinopathy in type 2 diabetes (T2D) which can influence the cardiovascular profile in these patients. Our aim was to study the relationship between hypothyroidism and the occurrence of cardiovascular events in patients with T2D.Method: It is a retrospective study, including 184 T2D patients, conducted in the department C of the National Institute of Nutrition of Tunis during the year 2021.<p class="abste...

Introduction: The number of elderly with cognitive decline has been increasing. Several studies have shown that diabetes is a risk factor for cognitive impairment. Chronic hyperglycemia is implicated, probably by promoting the development of cerebral microvascular disease but physiopathology is complicated.Methods: The study involved thirty-seven diabetic patients hospitalized in the department C of National Institute of Nutrition and Food Technology of ...